Head Clinical and Commercial Drug Substance Supply - #46603

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

We advance science so that we all have more time with the people we love.

Pharma Global Technical Operations (PT) is the organization that manufactures and delivers Roche’s groundbreaking therapies to 127 million patients around the world. PT is involved in producing every Roche medicine – from the development process through clinical trials – and continuing to product maturity. Our organization coordinates all aspects of production of Roche medicines in all disease areas and dosage forms.

Pharma Technical Development (PTD) is integral to Roche’s mission to develop innovative and transformative meaningful medicines for patients by applying leading technical expertise to design, develop, supply, and register clinical stage products globally.

Within PTD, Synthetic Molecules Technical Development (PTDC) leverages advanced science and technology to drive the development of synthetic molecules from first-in-human studies through commercialization. Based in Basel, Switzerland, our team of approximately 700 experts works collaboratively to bring our vision to life, delivering impactful solutions that support our mission and uphold our core values.

The Opportunity

In the position, you will provide strategic direction and leadership for Clinical and Commercial Drug Substance manufacturing, ensuring alignment with PTDC’s long-term vision. In doing so you will lead and oversee Clinical and Commercial Drug Substance manufacturing, ensuring efficiency, compliance, and innovation. You will also be accountable to:

• Drive the scale-up and transfer of Drug Substance processes for clinical and commercial supply
• Ensure safe, compliant, and cost-effective production of clinical and commercial batches
• Champion quality, regulatory compliance, and operational excellence, maintaining an "inspection-ready" state as well as promote a strong Safety, Health, and Environment (SHE) culture within the organization
• Drive operational excellence by embedding digital and data-driven strategies for process optimization and efficiency
• Anticipate and mitigate technical, operational, and scientific risks while fostering innovation in drug substance manufacturing
• Lead, coach, and develop a high-performing team, fostering a culture of accountability and professional growth as well as cross-functional collaboration with internal and external partners to drive process innovation
  
  

Who You Are

You bring significant experience in a leadership role within Synthetic Molecules clinical and commercial drug substance supply and enjoy shaping and navigating through complexities. With your strong creative leadership skills (according to the VACC model of Visionary, Architect, Coach, Catalyst), you build forward-looking perspectives and remove obstacles with a focus on developing people and expanding technical skills. Further, you bring:

• Outstanding knowledge of regulatory guidelines and standards for drug substance process development and manufacturing and cGMP and SHE requirements practices
• Consistent track record of developing diverse, high performing organizations and teams with high standards for scientific excellence, driving innovation and operational effectiveness
• Skilled in managing complex stakeholder relationships, leading transformative initiatives, and ensuring rapid, high-impact decision-making
• Strong business acumen, with the ability to proactively identify and resolve issues that influence business direction and drive changes within the industry or discipline
• Strategic thinking and problem-solving abilities, complemented by strong financial acumen and budget management experience
• Strong ability to drive robust, efficient, and scalable processes, optimizing speed, cost-effectiveness, and overall performance
  
  

If this exciting opportunity is for you we look forward to receiving your application.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.